Internet Explorer is not opening PDF files in the frame but ask to save it ?

Open Internet Explorer, Tools menu, Manage Add-ons
In the Manage Add-ons dialog, select in "Toolbars and Extensions"
Make sure Adobe Acrobat Control is Enabled. If it's disabled, enable the add-on and restart Internet Explorer.

PDF Links are not working in Google Chrome

By default, Chrome uses a built-in PDF viewer to open PDFs. If you've disabled the built-in PDF viewer,
Chrome will use Adobe Acrobat or Adobe Reader to display PDFs.
You can also choose to make Adobe Acrobat or Adobe Reader your default PDF viewer in Chrome. Here's how:

1.Enter chrome://plugins into your address bar.
2.Scroll down to either Adobe Acrobat or Adobe Reader. (You'll only see them if you have them installed.)
3.Click the Enable link.

Saving Document

Put your mouse cursor at the bottom of the page you get a popup window, or use "shift + Ctrl +S"